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32nd International Conference on Nanomedicine & Drug Delivery, will be organized around the theme “Future Innovations and new Developments in Nanomedicine and Nano based drug delivery system”
Nanomedicine-2023 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Nanomedicine-2023
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Drug delivery describes the method and approach to delivering drugs or pharmaceuticals and other xenobiotics to their site of action within an organism, with the goal of achieving a therapeutic outcome. The field of drug delivery has advanced dramatically in the past few decades, and even greater innovations are anticipated in the coming years. Biomedical engineers have contributed substantially to our understanding of the physiological barriers to efficient drug delivery and have also contributed to the development of several new modes of drug delivery that have entered clinical practice.
Nanomedicine will be based on the ability to build Nanorobots. In the future these Nanorobots could actually be programmed to repair specific diseased cells, functioning in a similar way to antibodies in our natural healing processes. The motivation for the new manipulation technology is the desire to enter the micro and Nanoworld not only by viewing but also acting, altering micro- and nanosized objects. A new era on medicine are expected to happen in the coming years. Due to the advances in the field of Nanotechnology, Nanodevice manufacturing has been growing gradually. The elimination of bacterial infections in a patient within minutes, instead of using treatment with antibiotics over a period of weeks.
The development of the smart drug delivery system (SDDS) is a revolution of nanotechnology in the pharmaceutical and medical fields. Nanomaterials through their enhanced target specificity, biodistribution, and plasma retention have overcome the therapeutic adverse effects of the conventional drug delivery system. The response-based intelligence of the system helps to release drug payloads released under specific pathological conditions. The development of an intelligent drug delivery system combines multiple approaches and multiple signal responses to improve their applicability in diagnosis as well as therapy
Nanomedicine will be based on the ability to build Nanorobots. In the future these Nanorobots could actually be programmed to repair specific diseased cells, functioning in a similar way to antibodies in our natural healing processes. The motivation for the new manipulation technology is the desire to enter the micro- and Nanoworld not only by viewing but also acting, altering micro- and nanosized objects. A new era on medicine are expected to happen in the coming years. Due to the advances in the field of Nanotechnology, Nanodevice manufacturing has been growing gradually. The elimination of bacterial infections in a patient within minutes, instead of using treatment with antibiotics over a period of weeks.
The computational studies in nanoparticles have demonstrated that there has been considerable progress in Nano and biotechnology in the last several years. However, several key challenges have also become apparent, including the need for a better understanding of nanoparticle behaviour in vivo and the development of more effective nanoparticle therapeutics. Computational efforts are becoming an important tool in addressing both of these challenges, as well as in generally facilitating and accelerating nanotechnology-based translational research. The Nanoinformatics has come out as a new research area that covers raw data management, analysis of the data derived from biomedical applications and simulation of nanoparticle interactions with biological systems depicting the integration of biology, nanotechnology and informatics to form the basis for computational Nanomedicine.
Nanomedicine has been developing rapidly in recent years, particularly in the development of novel Nano tools for medical diagnosis and treatment. For instance, a new trend is becoming prevalent in developing Nanosystems for simultaneous tumour diagnosis and therapy. A new terminology "Theranostics" has been frequently used and applied in pre-clinical research and trials. A Nanosystem can simultaneously achieve both cell targeted in vivo imaging and photothermal treatment of cancer. While achieving concurrent high spatial and temporal resolution of the lesions via cell targeting; special non-evasive treatments are implemented at the same time by various means, such as localized drug release, hyperthermia, and photo-thermal therapy. Inspired by these challenging problems in biomedical fields, the development of the nanotechnologies will be the key in addressing some of the critical issues in medicine, especially in early cancer diagnosis and treatment.
With the remarkable development of Nanotechnology in recent years, new drug delivery approaches based on the state-of-the-art nanotechnology have been receiving significant attention. Nanoparticles, an evolvement of nanotechnology, are increasingly considered as a potential candidate to carry therapeutic agents safely into a targeted compartment in an organ, particular tissue or cell. These particles are colloidal structures with a diameter less than 1,000 nm, and therefore can penetrate through diminutive capillaries into the cell’s internal machinery. This innovative delivery technique might be a promising technology to meet the current challenges in drug delivery. The different types of nanoparticles drug delivery systems under investigation and their prospective therapeutic applications, and also present a closer look at the advances, current challenges, and future direction of nanoparticles drug delivery systems.
The use of nanoscale materials and processes to address human disease is perhaps the most promising, considering that most complex downstream symptoms of disease are initiated by molecular level phenomena. Nanomedicine is defined as biological and medical intervention at the nanometer scale for the treatment, diagnosis, and increased understanding of biology and disease. Tremendous advances in the area of polymer synthesis and self-assembly have given rise to a new toolbox of engineered nanosized delivery and diagnostic agents that permit systemic and local administration, circulation in the bloodstream, and uptake and diffusion at the cellular and subcellular level.
Recent years have witnessed the rapid development of inorganic nanomaterials for medical applications. At present, nanomedicines-nanoparticles (NPs) destined for therapy or diagnosis purposes-can be found in a number of medical applications, including therapeutics and diagnosis agents .Pushing the limits of nanotechnology towards enhanced Nanomedicines will surely help to reduce side effects of traditional treatments and to achieve earlier diagnosis. The interplay between engineered nanomaterials and biological components is influenced by complex interactions which make predicting their biological fate and performance a nontrivial issue. We hope that both early-stage and experienced researchers will find it valuable for designing nanoparticles for enhanced bio-performance. Nanoemulsions have attracted great attention in research, dosage form design and pharmacotherapy. This is as a result of a number of attributes peculiar to nanoemulsions.
Nanotechnology is a rapidly growing field having potential applications in many areas. Nanoparticles have been studied for cell toxicity, immunotoxicity, and genotoxicity. Tetrazolium-based assays such as MTT, MTS, and WST-1 are used to determine cell viability. Different types of cell cultures, including cancer cell lines have been employed as in vitro toxicity models. Considering the potential applications of NPs in many fields and the growing apprehensions of FDA about the toxic potential of Nanoproducts, it is the need of the hour to look for new internationally agreed, free of bias toxicological models by focusing more on in vivo studies. The rapid expansion of nanotechnology promises to have great benefits for society, yet there is increasing concern that human and environmental exposure to engineered nanomaterials may result in significant adverse effects. The system was developed for Nanotoxicity assessment at single and multiple cell levels which can measure and compare the microscopic and macroscopic effects of nanoparticles interaction with cells, without interference from neighbouring cells' cues and also overall integrative effects produced by nanoparticles and cell–cell communication.