Nanomedicine and Drug Delivery

Nano toxicology is the study of the toxicity of nanomaterials. Because of quantum size effects and large surface area to volume ratio, nanomaterials have unique properties compared with their larger counterparts that affect their toxicity. Of the possible dangers, inhalation exposure appears to present the most concern, with animal studies showing pulmonary effects such as inflammation, fibrosis, and carcinogenicity for some nanomaterials. Skin contact and ingestion exposure are also a concern.

DNA nanotechnology is the design and manufacture of artificial nucleic acid structures for technical uses. In this field, nucleic acids are used as non-biological engineering materials for nanotechnology rather than as the carriers of genetic information in living cells. Researchers in the field have created static structures such as two- and three-dimensional crystal lattices, nanotubes, polyhedral, and arbitrary shapes, and functional devices such as molecular machines and DNA computers. The field is beginning to be used as a tool to solve basic science problems in structural biology and biophysics, including applications in X-ray crystallography and nuclear magnetic resonance spectroscopy of proteins to determine structures. Potential applications in molecular scale electronics and Nano medicine are also being investigated.

According to the World Health Organization (WHO), there will be 15 million new cases of cancer worldwide in 2020. More than 90% of cancer-related deaths occur by the spread of malignant cells to vital organs, a process called metastasis. Academia, Pharmaceutical and biotechnology companies are making substantial research investments in order to develop specific treatments that can destroy primary and secondary tumors, i.e. those resulting from metastasis to other organs. Nanotechnology in cancer treatments is already a reality providing a wide range of new tools and possibilities, from earlier diagnostics and improved imaging to better, more efficient, and more targeted therapies.

Nano Pharmaceutical Market report focuses on the major drivers and restraints for the key players. It also provides granular analysis of the market share, segmentation, revenue forecasts and geographic regions of the market.  The Nano Pharmaceutical Market research report is a professional and in-depth study on the current state of the Nano Pharmaceutical Industry.

Nanomedicine is a field that incorporates the studies related to Nano sized particles, their function and behavior with respect to different systems. The tremendous capabilities of nanoparticles have changed the perspective and scope of nanotechnology towards development into an adjuvant field for the remaining fields of life sciences. The role of nanotechnology in the field of pharmaceutics has tremendously changed the way of our understanding about drugs, Nano drugs or the use of nanoparticles as carrier of drug has become the basic fundamental or criteria for the production or design of a drug and advances in nanotechnology.

Nanotechnology is an important field of modern research dealing with design, synthesis, and manipulation of particle structures ranging from approximately 1-100 nm.

The session Design of Nanomedicine and Nanotechnology includes broad  topics like:  Carbon Nanotubes, Nanoparticles, Gold Nanoparticles, Silver Nanoparticles, Magnetic Nanoparticles, Nano Micro Particles, Nanocomposite Microspheres, Biosensors and Nano bioelectronics, Bio inspired materials and drug delivery and Nanobiomechanics and Nanomedicine.

To reach target cell, designing of Nano drugs are major aspects, where researcher interested or developing novel Nano drugs. Aimed and specially designed session for researchers developing Nano drugs for delivery of amino acids, Nucleic acids and proteins. The session Design of Nanodrugs includes: Novel Drugs to Nano drugs, Nano drugs for Cancer Therapy, Nano drugs for Veterinary Therapeutics, Nano drugs for Medical applications and Nano drugs for Herbal medicines and Cosmetics. Apart from Nano drugs, nanotechnology also aided in the development of therapeutics at the genetic level, wherein gene delivery methods are employed to attain a more precise therapeutic approach.

Nanotechnology mediated Tissue engineering is a branch a branch of biomedical engineering, which aims at the application of nanotechnology in tissue engineering mediated therapeutic techniques. Tissue engineering and regenerative medicine are concerned with the replacement or regeneration of cells, tissues (the focus of tissue engineers) or organs to restore normal biological function.

Nano pharmaceuticals deals with emerging new technologies for developing customized solutions for drug delivery systems. The drug delivery system positively impacts the rate of absorption, distribution, metabolism, and excretion of the drug or other related chemical substances in the body. In addition to this the drug delivery system also allows the drug to bind to its target receptor and influence that receptor’s signaling and activity. Pharmaceutical nanotechnology embraces applications of nanoscience to pharmacy as nanomaterials, and as devices like drug delivery, diagnostic, imaging and biosensor.

Theranostic nanomedicine is emerging as a promising therapeutic paradigm. It takes advantage of the high capacity of Nano platforms to ferry cargo and loads onto them both imaging and therapeutic functions. The resulting Nano systems, capable of diagnosis, drug delivery and monitoring of therapeutic response, are expected to play a significant role in the dawning era of personalized medicine, and much research effort has been devoted toward that goal.

As the science and technology of nanomedicine speed ahead, ethics, policy, and the law struggle to catch up also chases after it. It is important to proactively address the ethical, social and regulatory aspects of nanomedicine to minimize its adverse impacts on the environment and public health and to avoid a public backlash. In the next 10–15 years, nanotechnology is likely to revolutionize the practice of medicine and have a significant impact on human health. Nanotechnology is already contributing to the development of new drugs, biologics, and medical devices and the augmentation of existing therapeutics. Over 200 companies are involved in nanomedicine research and development. The U.S. Food and Drug Administration has approved nine different types of therapies that employ nanoscale materials, including products used for medical testing and imaging, drug delivery, wound healing, and bone and tissue repair. Discoveries and innovations in nanomedicine have occurred at a breath taking pace in just a short time, uses of nanotechnology in medicine have moved from laboratory testing, to clinical trials, to medical applications.